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How Does Dapoxetine Work?

  • By: Admin
  • Jun 25, 2021
How Does Dapoxetine Work?

This is a highly effective treatment for the male sexual disorder, premature ejaculation (PE), and is commonly used by men aged 18 to 64 years. These tablets were created to help men increase their ejaculation times by affecting the hormone, serotonin. This mechanism of action is similar to that of an anti-depressant medication, but due to the fast-acting formulation of this therapeutic, dapoxetine was better suited to being a sexual dysfunction medicine rather than an anti-depressant.

The active ingredient in these tablets is dapoxetine and it is this therapeutic ingredient that is classified as a selective serotonin reuptake inhibitor, or SSRI. When we feel happy, anxious or moody, it is the serotonin hormone that stabilizes these feelings. Moreover, this hormone also impacts other body processes, such as digestion, sleep or ejaculation, by affecting the communication between nerve and brain cells.

Following the communication of a chemical message, serotonin is typically reabsorbed by the nerve cells in what is known as a 'reuptake' of the hormone. By blocking this reuptake process, the levels of serotonin can subsequently be increased and thus, more readily available for influencing the physiological process of ejaculation. Dapoxetine (Priligy) tablets therefore work, through the above-mentioned process, to treat ejaculation problems by increasing the time to sexual climax.

How Does Dapoxetine Work to Treat PE?

A dapoxetine dosage is normally used by men who are experiencing symptoms of premature ejaculation and to be classified with this sexual disorder, there are certain criteria that have to be met:

  • An intravaginal latency time (IVLT) of less than two minutes
  • Ejaculation that occurs recurrently, with minimal sexual arousal, and sooner than the patient would prefer
  • Lack of control over ejaculation
  • Persistent symptoms of PE occurring for at least a period of six months
  • Interpersonal strain or problems as a consequence of the PE symptoms

For men who are experiencing all of the above criteria, a premature ejaculation treatment, such as dapoxetine 60 mg, can function to increase the levels of serotonin in the body, which can assist the symptoms of PE by:

  • Increasing the IVLT to an average of 3.8 minutes; ranging from 0.9 to 4.7 minutes (McCarty and Dinsmore, 2012)
  • Improving control over ejaculation
  • Improving ejaculation-related distress and other negative consequences
  • Improving sexual satisfaction

How Long Will Dapoxetine Work For?

Dapoxetine tablets are categorized as a fast-acting SSRI; this means that the therapeutic ingredients are rapidly absorbed by the body. These pills should ideally be taken at least one to three hours prior to sexual activity as this will give the medication sufficient time to work in the body before it is required to increase the time to ejaculation. The effects of dapoxetine can last for approximately 12 hours but this is dependent on aspects such as the medical condition of the patient and the dosage that is used, as well as many other factors.

Therapeutic benefit has been observed with the use of this premature ejaculation medication for up to 12 weeks, according to researchers. However, the long-term use of this medicine can also be associated with an increased risk of side effects, such as:

  • Nausea
  • Headaches
  • Dizziness
  • Decreased libido
  • Dry mouth
  • Insomnia
  • Erectile dysfunction
  • Diarrhea

As per a study by McMahon (2012), the incidences of adverse effects were reported as being dose-related. The most common adverse events were headaches (5.6% for the 30 mg dose, 8.8% for the 60 mg), nausea (11% for the 30 mg dose, 22.2% for the 60 mg dose) and dizziness (5.9% for the 30 mg dose, 10.9% for the 60 mg dose). Moreover, when taken as needed, the dapoxetine side effects, such as a decreased libido and sexual dysfunction, were shown to be very mild in nature (less than 1% and 4% of the clinical trial patients, respectively).

Does 30 mg and 60 mg Dapoxetine Work Differently?

The mode of action of dapoxetine remains the same, irrespective of the dosage, but it is the effects, of these doses on the body, that may vary. As previously mentioned, higher dosages of a medication can be related to a higher incidence of side effects. However, with that said, a higher dose can also be associated with greater therapeutic benefit.

In a clinical trial of 2614 men with moderate to severe symptoms of PE, a 30 mg dosage was revealed to increase the time to ejaculation to a mean 2.78 minutes, as compared to a mean of 3.32 minutes for the 60 mg dose of the premature ejaculation pills. This was following a three-month treatment period, which indicated an IVTL of an average 1.75 minutes for the placebo (inactive treatment) group of the study population.

Furthermore, according to the previously mentioned study by McCarty and Dinsmore, the half-life (time taken for the removal of half of the medication from the body) is longer for the 60 mg dosage (21.9 hours), as compared to a half-life of 18.7 hours for the 30 mg dose. This further indicates greater efficacy of the higher dosages through a prolonged duration of action.

Many men are in favor of the 60 mg dose of this medication, as per a dapoxetine review, and this is also a frequently reported or standard dose of treatment. But for men who are at a greater risk of developing adverse effects (such as seniors or those with renal and/ or hepatic impairment), a 30 mg dosage may be a better suited when initiating dapoxetine treatment. You can easily find dapoxetine for sale, in both 30 mg and 60 mg dosages, through secure online pharmacies.

Buy Dapoxetine Last Longer in Bed!

A safe and secure online pharmacy is quickly becoming the norm for buying medications because of its ease and convenience of use, in addition to the vast other benefits these platforms offer. The internet pharmacy phenomenon is particularly useful for those with sensitive issues, such as premature ejaculation, as they provide a discreet means of acquiring treatment.

You can conveniently buy dapoxetine online via our secure platform, whilst maintaining your privacy and with a level of anonymity that would typically encourage patients to seek information about medications (that they would otherwise feel too ashamed to ask a general practitioner about).

Buy dapoxetine pills through our established internet pharmacy and join the millions of men who use this safe and effective FDA approved treatment to last longer in bed.

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